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ZINC13000658

ZINC13000658 is a METTL family inhibitor with significant anti-proliferative effects in various tumor cells, inducing G1 phase cell cycle arrest and apoptosis. Its IC50 values against HepG2 and SNU-449 cells are 5.632 μM and 6.184 μM respectively. Its mechanism of action may be related to inhibiting the activities of multiple methyltransferases such as METTL1/3/6/16/18, and it can be applied to basic research of various cancers.

Product Specifications

CAS Number

1324070-76-9

Purity

99.74% (May vary between batches)

Smiles

O=C1C=C (C (=O) NCCN2C=CC=3C=C (OC) C=CC32) C=4C=CC=CC4N1

Molecular Formula

C21H19N3O3

Molecular Weight

361.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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