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MKP10241

MKP10241 is an orally bioavailable GPR119 agonist that increases cAMP levels in GPR119-expressing cell lines with an EC50 of 3.7 nM. It significantly reduces blood glucose and glycated hemoglobin (HbA1c) levels in acute and chronic diabetic mouse models. It also exhibits favorable pharmacological activities in acute and chronic obesity models and MASH rodent models.

Product Specifications

CAS Number

2137977-29-6

Purity

99.79% (May vary between batches)

Smiles

FC1=C (C2=CN3C (=N2) SC (O[C@@H] (C) C4CCN (CC4) C=5N=CC (CC) =CN5) =N3) C=CC (S (C) (=O) =O) =C1

Molecular Formula

C24H27FN6O3S2

Molecular Weight

530.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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