MSU-44147
MSU-44147 is a small-molecule inhibitor that targets the membrane transport protein MmpL3 in Mycobacterium abscessus. MSU-44147 exhibits selective anti-mycobacterial activity and low cytotoxicity toward eukaryotic cells. By inhibiting MmpL3-mediated lipid transport, MSU-44147 disrupts cell wall synthesis and biofilm formation, and exhibits bactericidal activity against intracellular bacteria; simultaneously, it produces additive or synergistic effects when used in combination with various antibiotics.
Product Specifications
CAS Number
3105177-29-2
Purity
99.81% (May vary between batches)
Smiles
O=C (NCCC1=CC=C (C=C1) C (F) (F) F) C2 (C) CCCCC2
Molecular Formula
C17H22F3NO
Molecular Weight
313.36
Storage Conditions
-20°C
Notes
For research use only.
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