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PTP1B-IN-33

PTP1B-IN-33 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 2.45 μM against human PTP1B, showing more than 20-fold selectivity over SHP2. It enhances π-alkyl interactions with PTP1B, thereby promoting closure of the WPD loop. PTP1B-IN-33 can be used in studies on cancer, diabetes, and autoimmune deficiency diseases.

Product Specifications

CAS Number

77500-30-2

Purity

99.93% (May vary between batches)

Smiles

O=C (NC=1C=CC=CC1) C=2OC (=CC2) C (=O) NC=3C=CC=CC3

Molecular Formula

C18H14N2O3

Molecular Weight

306.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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