PTP1B-IN-33
PTP1B-IN-33 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 2.45 μM against human PTP1B, showing more than 20-fold selectivity over SHP2. It enhances π-alkyl interactions with PTP1B, thereby promoting closure of the WPD loop. PTP1B-IN-33 can be used in studies on cancer, diabetes, and autoimmune deficiency diseases.
Product Specifications
CAS Number
77500-30-2
Purity
99.93% (May vary between batches)
Smiles
O=C (NC=1C=CC=CC1) C=2OC (=CC2) C (=O) NC=3C=CC=CC3
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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