Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

M6766

M6766 is a selective and potent inhibitor of endoplasmic reticulum oxidoreductase 1α (ERO1α), exhibiting an IC50 of 1.4 uM and a KD of 1.1 uM. It also inhibits ERO1β with an IC50 of 7.2 uM. M6766 exerts its inhibitory effect by binding to the flavin adenine dinucleotide (FAD) -binding pocket of ERO1α. Functionally, M6766 suppresses granule secretion, αIIbβ3 integrin activation, Ca2+ mobilization, and platelet aggregation. It serves as a significant chemical probe for investigating the molecular pathways of arterial thrombosis and neurological disorders, such as ischemic stroke.

Product Specifications

CAS Number

696628-90-7

Purity

99.17% (May vary between batches)

Smiles

N#CC=1C2=NC=3C=CC=CC3N2C (SC4=NN=CN4C) =C5C1CCCC5

Molecular Formula

C19H16N6S

Molecular Weight

360.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Guinea pig Dermatan sulfate ELISA Kit
MBS753554-01 48 Well

Guinea pig Dermatan sulfate ELISA Kit

Sign In for Pricing
View Details
Guinea pig Dermatan sulfate ELISA Kit
MBS753554-02 96 Well

Guinea pig Dermatan sulfate ELISA Kit

Sign In for Pricing
View Details
Guinea pig Dermatan sulfate ELISA Kit
MBS753554-03 5x 96 Well

Guinea pig Dermatan sulfate ELISA Kit

Sign In for Pricing
View Details
Guinea pig Dermatan sulfate ELISA Kit
MBS753554-04 10x 96 Well

Guinea pig Dermatan sulfate ELISA Kit

Sign In for Pricing
View Details
Pyr-4MbNA
J-1295.0250 250.0mg

Pyr-4MbNA

Sign In for Pricing
View Details
MAP4K4 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, HPK/GCK-like Kinase HGK, HGK, KIAA0687, MAPK/ERK Kinase Kinase Kinase 4, MEK Kinase Kinase 4, MEKKK 4, MEKKK4, Nck-interacting Kinase, NIK) (APC)
129389-APC 100 µL

MAP4K4 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, HPK/GCK-like Kinase HGK, HGK, KIAA0687, MAPK/ERK Kinase Kinase Kinase 4, MEK Kinase Kinase 4, MEKKK 4, MEKKK4, Nck-interacting Kinase, NIK) (APC)

Sign In for Pricing
View Details