SB405483
SB405483 is a CRBN (cereblon) orthosteric ligand-binding enhancer that promotes the ubiquitination and proteasomal degradation of CRBN substrates (such as CK1α, Wee1, and IKZF1/3) by stabilizing the CRBN protein conformation and enhancing its binding affinity for substrates. SB405483 can be used in cancer research, such as in multiple myeloma and acute myeloid leukemia.
Product Specifications
Purity
99.70% (May vary between batches)
Smiles
O=C (NC1=C (O) C=C (C#N) C=C1) NC (N=CC=C2) =C2OCC3=CC=CC=C3
Molecular Formula
C20H16N4O3
Molecular Weight
360.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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