HDAC6-IN-65
HDAC6-IN-65 is a highly selective histone deacetylase 6 inhibitor with a half-maximal inhibitory concentration (IC50) of 0.9 nM against HDAC6, and also exhibits a certain inhibitory activity against HDAC3 with a corresponding IC50 value of 39.4 nM. HDAC6-IN-65 can induce the accumulation of acetylated α-tubulin (ac-tubulin) and acetylated histone H3 (ac-histone H3, a specific marker for class I HDAC inhibition) in Neuro-2a cells, and is currently available as a research tool for mechanism and experimental studies related to melanoma .
Product Specifications
CAS Number
3028442-70-5
Purity
99.69% (May vary between batches)
Smiles
O=C (NO) C1=CC=C (C=C1) CN (CC=2C=NC=CC2) S (=O) (=O) C=3C=CC=CC3Cl
Molecular Formula
C20H18ClN3O4S
Molecular Weight
431.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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