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HDAC6-IN-65

HDAC6-IN-65 is a highly selective histone deacetylase 6 inhibitor with a half-maximal inhibitory concentration (IC50) of 0.9 nM against HDAC6, and also exhibits a certain inhibitory activity against HDAC3 with a corresponding IC50 value of 39.4 nM. HDAC6-IN-65 can induce the accumulation of acetylated α-tubulin (ac-tubulin) and acetylated histone H3 (ac-histone H3, a specific marker for class I HDAC inhibition) in Neuro-2a cells, and is currently available as a research tool for mechanism and experimental studies related to melanoma .

Product Specifications

CAS Number

3028442-70-5

Purity

99.69% (May vary between batches)

Smiles

O=C (NO) C1=CC=C (C=C1) CN (CC=2C=NC=CC2) S (=O) (=O) C=3C=CC=CC3Cl

Molecular Formula

C20H18ClN3O4S

Molecular Weight

431.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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