ARUK2010489
ARUK2010489 (Compound 23) is a potent, selective, and brain-penetrant NUAK1 inhibitor with a pIC50 of 8.7, also exhibiting partial inhibitory activity against CDK2, CDK4, and CDK6 at micromolar concentrations, and it is applied in neurological disease research, including mechanistic studies related to Alzheimer’s disease.
Product Specifications
Purity
99.85% (May vary between batches)
Smiles
CC (C) N1CCN (C2=CC=C (NC3=NC (OCC4CC4) =C5C=CNC5=N3) C=C2) CC1
Molecular Formula
C23H30N6O
Molecular Weight
406.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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