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HJB97

HJB97 is used for the design of potential PROTAC BET degrader. It also has antitumor activity. HJB97 is a high-affinity inhibitor of BET (Kis: 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), 1.0 nM (BRD4 BD2), respectively) .

Product Specifications

CAS Number

2093391-24-1

Smiles

CCn1nc (cc1Nc1nc (nc2[nH]c3cc (-c4c (C) noc4C) c (OC) cc3c12) C (=O) NC) C1CC1

Molecular Formula

C26H28N8O3

Molecular Weight

500.55

Storage Conditions

-20°C

Notes

For research use only.

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