Al-28
Al-28 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. Al-28 can be used in the preparation of liposomes[1].
Product Specifications
CAS Number
3055572-07-8
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/al-28.html
Purity
97.37
Smiles
CCCCCCCCCCCCSSCCOC(CCNCCCN(C)CCCN(CCC(OCCSSCCCCCCCCCCCC)=O)CCC(OCCSSCCCCCCCCCCCC)=O)=O
Molecular Formula
C58H115N3O6S6
Molecular Weight
1142.94
References & Citations
[1]Schlich, et al. "Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles." Bioengineering & Translational Medicine 6.2 (2021) : e10213.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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