BW 348U87
BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model[1].
Product Specifications
CAS Number
[127142-14-7]
Product Name Alternative
348U87
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bw-348u87.html
Purity
99.73
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C/C(C1=CC=CC=N1)=N\NC(NNC(NC2=C(C=CC=C2)Cl)=S)=S
Molecular Formula
C15H15ClN6S2
Molecular Weight
378.90
References & Citations
[1]Spector T, et al., Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovir. Antimicrob Agents Chemother. 1992 May;36 (5) :934-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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