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BW 348U87

BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model[1].

Product Specifications

CAS Number

[127142-14-7]

Product Name Alternative

348U87

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bw-348u87.html

Purity

99.73

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C/C(C1=CC=CC=N1)=N\NC(NNC(NC2=C(C=CC=C2)Cl)=S)=S

Molecular Formula

C15H15ClN6S2

Molecular Weight

378.90

References & Citations

[1]Spector T, et al., Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovir. Antimicrob Agents Chemother. 1992 May;36 (5) :934-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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