NCC007
Product Specifications
UNSPSC Description
NCC007 is a dual casein kinase Iα (CKIα) and δ (CKIδ) inhibitor with IC50s of 1.8 and 3.6 μM, respectively. NCC007 can be used in research of modulating mammalian circadian rhythms[1].
Target Antigen
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Stem Cell/Wnt
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ncc007.html
Purity
99.73
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN(C)CCNC1=NC2=C(N=CN2C(C)C3CC3)C(NCC4=CC(C(F)(F)F)=CC=C4)=N1
Molecular Weight
447.50
References & Citations
[1]Lee JW, et al. Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Iα and δ. J Med Chem. 2019 Feb 28;62(4):1989-1998.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128677/NCC007-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128677/NCC007-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2342583-66-6
Available Sizes
Curated Selection
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