Azadirachtin I

Azadirachtin I is an insecticide that targets pathways related to insect growth and development, such as the ecdysone signaling pathway and the chitin synthesis pathway. It disrupts the growth and development of insect larvae by interfering with molting and pupation, inhibiting chitin synthesis, and impairing gut function, which increases insect mortality and reduces adult reproductive capacity. Azadirachtin I is promising for research on agricultural pests, including those in the Lepidoptera and Coleoptera orders.