Propionylpromazine-d6 (hydrochloride)

Propionylpromazine-d6 (hydrochloride) is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].

Product Specifications

CAS Number

[1262770-67-1]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.78

Solubility

10 mM in DMSO|H2O : 8.33mg/mL (ultrasonic)

Smiles

[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCCN1C2=CC(C(CC)=O)=CC=C2SC3=CC=CC=C31.Cl

Molecular Formula

C20H19D6ClN2OS

Molecular Weight

382.98

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Tyers, Mike, et al. Method for treating a brain cancer with ifenprodil. US8058243.