TLR7/8/9 antagonist 2
TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.
Product Specifications
CAS Number
2920729-91-3
Smiles
N=1C=C (C=C (C1C2CCN (C=3C=C (N=C4C3C=NN4C) C) CC2) C) N5CCNCC5
Molecular Formula
C23H31N7
Molecular Weight
405.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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