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EBET-1593

EBET-1593 is a BETPROTAC degrader that facilitates the ubiquitination and degradation of BET proteins. It serves as the primary payload and can be utilized in the synthesis of ADCs, such as 84-EBET, which exhibits antitumor activity against pancreatic ductal adenocarcinoma.

Product Specifications

CAS Number

3031540-97-0

Smiles

O=C1NC (=O) CCN1C2=CC (C#CCNC3 (C) CCN (CC3) C4CCN (C=5N=C6C=CC (=CC6=C (N5) C (OC7CC7) (C=8C=CC=CC8) CO) C9=CN (C (=O) C=%10NC=CC9%10) C) CC4) =CC=C2OC

Molecular Formula

C52H57N9O6

Molecular Weight

904.09

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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