PROTAC CDK4/6/9 degrader 1
PROTACCDK4/6/9 degrader 1 is a PROTAC degrader targeting CDK4/6/9. It effectively degrades CDK4, CDK6, and CDK9 within triple-negative breast cancer (TNBC) cells, thereby inhibiting their proliferation. Additionally, PROTACCDK4/6/9 degrader 1 induces G1 phase arrest, promotes apoptosis, and suppresses cell migration and invasion in TNBC cells. This compound is useful for researching triple-negative breast cancer (TNBC) .
Product Specifications
CAS Number
3064994-97-1
Smiles
O=C1C2=CC=C (C=C2C (=O) N1C3C (=O) NC (=O) CC3) N4CCN (C (=O) CN5CCC (CN6CCN (CC (=O) C7=CC=C (C=C7) NC=8N=CC=9C=C (C (=O) N (C) C) N (C9N8) C%10CCCC%10) CC6) CC5) CC4
Molecular Formula
C51H62N12O7
Molecular Weight
955.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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