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VARS1-IN-2

VARS1-IN-2 (Compound 2901) is a specific inhibitor of VARS1 with a Kd of 0.014 μM. It does not affect VARS1 expression at the mRNA or protein levels. The compound exhibits anti-prostate cancer activity primarily by disrupting the tRNA aminoacylation activity of VARS1, rather than altering its expression.

Product Specifications

CAS Number

667914-07-0

Smiles

O=C1NC=2C=CC=CC2C1=C3SC4=NC=5C=6C=CC=CC6CCC5C (C=7SC=CC7) N4C3=O

Molecular Formula

C26H17N3O2S2

Molecular Weight

467.56

Storage Conditions

-20°C

Notes

For research use only.

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