TIPARP-IN-1
TIPARP-IN-1 (Compound 15) is a selective inhibitor of PARP7 (TIPARP, also known as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inducible PARP) with an IC50 value of 2.15 nM. By inhibiting TIPARP, TIPARP-IN-1 can restore the IFN signaling pathway in tumors. In the tumor microenvironment, it selectively activates anti-tumor immune responses while avoiding the systemic production of cytokines. TIPARP-IN-1 is applicable for research in head and neck squamous cell carcinoma.
Product Specifications
CAS Number
3106183-96-1
Smiles
C (=O) ([C@H]1C[C@@H] (CC=2C=C (C (F) (F) F) C (=O) NC2) C1) N3C[C@@H] (C) N (CC3) C=4N=CC (C (F) (F) F) =CN4
Molecular Formula
C22H23F6N5O2
Molecular Weight
503.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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