PRMT5-MTA-IN-7
PRMT5-MTA-IN-7 (Compound 14) is a selective inhibitor of PRMT5-MTA. It exhibits KD values of 236 nM for PRMT5-MTA and 2.84 μM for PRMT5-SAM, with IC50 values of 4.08 μM and 13.6 μM, respectively. PRMT5-MTA-IN-7 selectively inhibits the proliferation of MTAP-deficient cancer cells and is applicable in colon cancer research.
Product Specifications
CAS Number
303969-88-2
Smiles
O=C1NC (=O) N (C=2N=C (SCC (O) CO) N (C12) CC3=CC=C (C=C3) C) C
Molecular Formula
C17H20N4O4S
Molecular Weight
376.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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