ML901
ML901 is an antimalarial compound with an IC50 value of 2 nM against Plasmodium parasites. It functions by selectively inhibiting Plasmodium falciparum tyrosine tRNA synthetase (PfYRS) through a "reaction hijacking" mechanism. ML901 demonstrates full life-cycle killing activity in mouse models of malaria and can be used for studying Plasmodium infections.
Product Specifications
CAS Number
2226228-02-8
Smiles
O[C@H]1[C@H] (N2C=3C (C (OC (F) F) =N2) =C (N) N=CN3) O[C@H] (COS (N) (=O) =O) [C@H]1O
Molecular Formula
C11H14F2N6O7S
Molecular Weight
412.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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