ISR activator 3
ISR activator 3 (Compound cc81) is the active metabolite of A8. It activates the integrated stress response (ISR) by binding to RIG-I (KD≈ 0.55 μM) without inducing lipid droplet clearance. Additionally, ISR activator 3 enhances the interferon response under viral mimic signaling. This compound is applicable in studies of neurodegenerative diseases and immune stress.
Product Specifications
CAS Number
332950-12-6
Smiles
O=C (OCC) C1=C (SC=C1C=2C=CC=CC2) NC (=O) C=3SC4=NC (=CC (=C4C3N) C) C
Molecular Formula
C23H21N3O3S2
Molecular Weight
451.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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