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ISR activator 3

ISR activator 3 (Compound cc81) is the active metabolite of A8. It activates the integrated stress response (ISR) by binding to RIG-I (KD≈ 0.55 μM) without inducing lipid droplet clearance. Additionally, ISR activator 3 enhances the interferon response under viral mimic signaling. This compound is applicable in studies of neurodegenerative diseases and immune stress.

Product Specifications

CAS Number

332950-12-6

Smiles

O=C (OCC) C1=C (SC=C1C=2C=CC=CC2) NC (=O) C=3SC4=NC (=CC (=C4C3N) C) C

Molecular Formula

C23H21N3O3S2

Molecular Weight

451.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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