VK4-116
VK4-116 (Compound 19) is a selective dopamine D3 receptor (D3R) antagonist with a Ki of 6.84 nM. It significantly inhibits oxycodone-induced hyperactivity and locomotor sensitization in mouse models. Additionally, VK4-116 pretreatment suppresses the acquisition of oxycodone-induced conditioned place preference (CPP) in rat models.
Product Specifications
CAS Number
1982347-43-2
Smiles
O=C (NCCC (O) CN1CCN (C2=CC (=CC (Cl) =C2OC) CC) CC1) C3=CC=4C=CC=CC4N3
Molecular Formula
C26H33ClN4O3
Molecular Weight
485.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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