Antituberculosis agent-17

Antituberculosis agent-17 (compound 21) is a potent and selective antituberculosis agent. It demonstrates excellent antituberculosis activity against Mycobacterium tuberculosis H37Rv, multidrug-resistant (MDR) strains, and extensively drug-resistant (XDR) strains, with MIC values ranging from 0.2 to 0.78 μM. Its selectivity is higher for Mycobacterium tuberculosis than for certain non-tuberculous mycobacteria and bacteria. Antituberculosis agent-17 is applicable in tuberculosis research.