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BrP-LPA sodium

BrP-LPA sodium is a broad-spectrum antagonist of lysophosphatidic acid (LPA), demonstrating antagonistic activity towards LPA1 (IC50 = 4520 nM), LPA2 (IC50 = 468 nM), LPA3, and LPA4. Additionally, BrP-LPA sodium exhibits partial agonistic activity at LPA5 with an EC50 of 1282 nM. It also acts as an ATX inhibitor and effectively inhibits the migration and invasion of breast cancer cells. In mouse xenograft models of breast cancer, BrP-LPA sodium induces tumor regression and anti-angiogenic effects. This compound is applicable for breast cancer research.

Product Specifications

CAS Number

944265-88-7

Smiles

O (C[C@H] (CC (P (=O) (O) O) Br) O) C (CCCCCCCCCCCCCCC) =O.[Na]

Molecular Formula

C20H41BrNaO6P

Molecular Weight

511.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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