Gonyautoxin III
Gonyautoxin III (GTX-III) is a paralytic shellfish toxin. It inhibits voltage-gated sodium channels at the axonal level, with an IC50 value of 14.9 nM, thereby disrupting the conduction of nerve impulses. Gonyautoxin III also exhibits cytotoxic activity against mouse neuroblastoma cells and is applicable in research on cancer and neurological diseases.
Product Specifications
CAS Number
60537-65-7
Smiles
OC1 (O) [C@]23[C@] ([C@H] (COC (N) =O) N=C (N) N2C[C@@H]1OS (=O) (=O) O) (N=C (N) N3) [H]
Molecular Formula
C10H17N7O8S
Molecular Weight
395.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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