Dehydrofalcarinol
Dehydrofalcarinol is a polyacetylene compound identified in Desmanthodium guatemalense. It exhibits potent inhibitory activity against cell lines MDA-MB-231, MDA-MB-157, BT-549, HCC1806, MDA-MB-468, and MDA-MB-453 with IC50 values of 0.051, 0.059, 0.22, 0.3, 0.85, and 2.8 μM, respectively. Its anticancer efficacy is dependent on 11β-hydroxysteroid dehydrogenase type 17 (17β-HSD) . Dehydrofalcarinol is applicable in the study of triple-negative breast cancer.
Product Specifications
CAS Number
36150-08-0
Smiles
C (#CC/C=C\CCCCCC=C) C#C[C@@H] (C=C) O
Molecular Formula
C17H22O
Molecular Weight
242.36
Storage Conditions
-20°C
Notes
For research use only.
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