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MPXV p37 protein-IN-1

MPXV p37 protein-IN-1 is a potent and orally effective inhibitor of the monkeypox virus (MPXV) p37 protein. It exhibits significant antiviral activity against MPXV, with an EC50 of 12.14 nM, and shows low cytotoxicity (CC50= 304.63 μM) . In mice, MPXV p37 protein-IN-1 demonstrates low toxicity and good tolerability. This compound can be utilized for research into anti-monkeypox virus drugs.

Product Specifications

CAS Number

3096845-40-5

Smiles

O=C1[C@@]2 ([C@]3 ([C@]4 ([C@] (C4) ([C@@] ([C@@]2 (C (=O) N1NC (NC5=CC (F) =C (F) C=C5) =S) [H]) (C=C3) [H]) [H]) [H]) [H]) [H]

Molecular Formula

C18H15F2N3O2S

Molecular Weight

375.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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