LT-104A
LT-104A is a potent PDE4 inhibitor that elevates intracellular cAMP levels (EC50 = 1.9 μM) and inhibits PDE4D3 activity (IC50 = 9.3 μM) . It activates the cAMP-PKA-CREB anti-inflammatory pathway and suppresses NF-κB-related gene expression (Il1b and Nos2), making it applicable for research in inflammation-related diseases.
Product Specifications
CAS Number
2574572-03-3
Smiles
C (OC (=O) C=1C2=C (C=CC1) C=CC=C2) [C@@H]3[C@H] (OC[C@@H]3CC4=CC (OC) =C (OC) C=C4) C5=CC (OC) =C (OC) C=C5
Molecular Formula
C33H34O7
Molecular Weight
542.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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