CKBA
CKBA, a derivative of AKBA, acts as an acetyl-CoA carboxylase 1 (ACC1) inhibitor with an IC50 of 5.02 μM. It inhibits Th17 cell differentiation, displaying IC50 values of 3.28 μM in mouse cells and 3.61 μM in human cells. CKBA ointment significantly alleviates psoriasis-like inflammation in mice and can be used for psoriasis research.
Product Specifications
CAS Number
1786406-66-3
Smiles
C[C@]12[C@@] ([C@]3 (C) [C@@] (CC1) ([C@] (C (O) =O) (C) [C@H] (OC (=O) C4CCCCC4) CC3) [H]) (C (=O) C=C5[C@@]2 (C) CC[C@]6 (C) [C@]5 ([C@@H] (C) [C@H] (C) CC6) [H]) [H]
Molecular Formula
C37H56O5
Molecular Weight
580.85
Storage Conditions
-20°C
Notes
For research use only.
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