5-HT4 antagonist 1

5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6.

Product Specifications

CAS Number

[261766-73-8]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-HT4_antagonist_1.html

Purity

98.95

Solubility

DMSO : 20 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 60°C)

Smiles

O=C(C1=C2OCCOC2=CC=C1)NCC3CCN(CCCS(=O)(N4CCN(C)CC4)=O)CC3

Molecular Formula

C23H36N4O5S

Molecular Weight

480.62

References & Citations

[1]Clark RD, et al. Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification. Bioorg Med Chem Lett. 2005 Mar 15;15 (6) :1697-700.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Apolipoprotein D

Available Sizes

Curated Selection

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