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Angustilongine M

Angustilongine M is a microtubule-targeting antitumor alkaloid with an IC50 of 0.2 μM against HT-29 cells. It induces G0/G1 phase cell cycle arrest and mitochondrial apoptosis by promoting microtubule polymerization. Angustilongine M shows potential for research in colorectal and other solid tumors.

Product Specifications

CAS Number

2732914-43-9

Smiles

C[C@H]1C=2C=3C4=C (N (C) C3C=CC2O[C@]5 ([C@@]1 ([C@]6 ([C@@] (CO5) ([C@@]7 (CC8=C ([C@] (C6) (N7C) [H]) N (C) C=9C8=CC=CC9) [H]) [H]) [H]) [H]) [H]) [C@]%10 ([N@@]%11[C@@] (C4) ([C@H] (CO) [C@] (C%10) (/C (=C\C) /C%11) [H]) [H]) [H]

Molecular Formula

C41H48N4O3

Molecular Weight

644.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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