EGFR/COX-2-IN-2

EGFR/COX-2-IN-2 (Compound 10a) is a dual inhibitor targeting the epidermal growth factor receptor (EGFR) with an IC50 of 6.0 μM and cyclooxygenase-2 (COX-2) with an IC50 of 50 μM. It induces cell cycle arrest in the S phase and triggers apoptosis. EGFR/COX-2-IN-2 holds potential for research in cancer and inflammation-related diseases.