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KMR-206

KMR-206 is a potent and selective PARP7 inhibitor with an IC50 of 13.7 nM. It enhances the expression of STAT1 and phosphorylated Tyr701 site STAT1 (pSTAT1) . KMR-206 induces STING degradation and elevates type I IFN receptor levels, showing anticancer activity against lung adenocarcinoma and is applicable in colon cancer research.

Product Specifications

CAS Number

2992741-10-1

Smiles

N#CC1=CN=C (C=C1) N2CCN (C (=O) C3=CC (=CC=C3F) CC4=NNC (=O) C=5C=CC (C#CC) =CC54) CC2

Molecular Formula

C29H23FN6O2

Molecular Weight

506.54

Storage Conditions

-20°C

Notes

For research use only.

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