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MU876

MU876 (Compound 32) is an MUS81 inhibitor with an IC50 of 0.5 μM. It effectively inhibits MUS81-dependent homologous recombination (HR) and break-induced replication (BIR) pathways. MU876 enhances the sensitivity of cancer cells to DNA-damaging agents like Cisplatin by impairing their ability to repair DNA damage. This compound is applicable in cancer chemotherapy research.

Product Specifications

CAS Number

1208829-24-6

Smiles

O=C1N=C (NC (=C1) C) N2N=C (C=C2NC (=O) C3=NOC (=C3) C=4C=CC=CC4) C=5C=CC=CC5

Molecular Formula

C24H18N6O3

Molecular Weight

438.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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