MU876
MU876 (Compound 32) is an MUS81 inhibitor with an IC50 of 0.5 μM. It effectively inhibits MUS81-dependent homologous recombination (HR) and break-induced replication (BIR) pathways. MU876 enhances the sensitivity of cancer cells to DNA-damaging agents like Cisplatin by impairing their ability to repair DNA damage. This compound is applicable in cancer chemotherapy research.
Product Specifications
CAS Number
1208829-24-6
Smiles
O=C1N=C (NC (=C1) C) N2N=C (C=C2NC (=O) C3=NOC (=C3) C=4C=CC=CC4) C=5C=CC=CC5
Molecular Formula
C24H18N6O3
Molecular Weight
438.45
Storage Conditions
-20°C
Notes
For research use only.
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