SOS1-IN-22
SOS1-IN-22 is an inhibitor of the non-heptakinase homologue (SOS1) . It effectively prevents the formation of the KRAS-G12C/SOS1 complex with an IC50 value of 40.28 nM. Additionally, SOS1-IN-22 reduces the phosphorylation levels of ERK. This compound is applicable in cancer research, including studies on pancreatic and appendiceal cancers.
Product Specifications
CAS Number
3092445-74-1
Smiles
N ([C@H] (C) C1=C (F) C (C (F) F) =CC=C1) C2=C3C (C (C) (C) C (=O) N (C3) C4CCOCC4) =NC (C) =N2
Molecular Formula
C24H29F3N4O2
Molecular Weight
462.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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