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SB 203186

SB 203186 is an exceptionally potent and highly selective indole-based 5-HT4 receptor antagonist (Ki = 0.2 nM) . It completely blocks 5-HT4-mediated depolarization and cholinergic signal amplification in both central and peripheral neurons at picomolar levels, widely used to investigate the pathogenesis of gastrointestinal smooth muscle motility disorders and arrhythmias.

Product Specifications

CAS Number

135938-17-9

Purity

98.25% (May vary between batches)

Smiles

O=C (OCCN1CCCCC1) C2=CNC=3C=CC=CC32

Molecular Formula

C16H20N2O2

Molecular Weight

272.34

Storage Conditions

-20°C

Notes

For research use only.

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