SB 203186
SB 203186 is an exceptionally potent and highly selective indole-based 5-HT4 receptor antagonist (Ki = 0.2 nM) . It completely blocks 5-HT4-mediated depolarization and cholinergic signal amplification in both central and peripheral neurons at picomolar levels, widely used to investigate the pathogenesis of gastrointestinal smooth muscle motility disorders and arrhythmias.
Product Specifications
CAS Number
135938-17-9
Purity
98.25% (May vary between batches)
Smiles
O=C (OCCN1CCCCC1) C2=CNC=3C=CC=CC32
Molecular Formula
C16H20N2O2
Molecular Weight
272.34
Storage Conditions
-20°C
Notes
For research use only.
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