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NT-0527

NT-0527 is a selective, orally active, and brain-permeable NLRP3 inflammasome inhibitor that inhibits NLRP3-induced IL-1β in human whole blood (IC50 = 0.79 ± 0.4 μM), and can be used for the study of neuroinflammatory diseases.

Product Specifications

CAS Number

2771019-10-2

Purity

99.90% (May vary between batches)

Smiles

O=C1C2=CC=C (Cl) C=C2C3 (CN1CC (=O) NC4=NC=C (F) C=N4) CC3

Molecular Formula

C17H14ClFN4O2

Molecular Weight

360.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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