NT-0527
NT-0527 is a selective, orally active, and brain-permeable NLRP3 inflammasome inhibitor that inhibits NLRP3-induced IL-1β in human whole blood (IC50 = 0.79 ± 0.4 μM), and can be used for the study of neuroinflammatory diseases.
Product Specifications
CAS Number
2771019-10-2
Purity
99.90% (May vary between batches)
Smiles
O=C1C2=CC=C (Cl) C=C2C3 (CN1CC (=O) NC4=NC=C (F) C=N4) CC3
Molecular Formula
C17H14ClFN4O2
Molecular Weight
360.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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