CV2a
CV2a is a 14-3-3-directed molecular glue-based PROTAC that selectively targets the ERα protein complex, with an EC50 of 0.10 μM. It facilitates the recruitment of VHL to the 14-3-3/ERα complex and enhances the potent polyubiquitination of the 14-3-3ζ/ERα complex.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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