KAT6-IN-4

KAT6-IN-4 (Compound Example 2) is a selective inhibitor of lysine acetyltransferase 6 (KAT6) . It inhibits the transcription of oncogenes such as ERα. In ER+/HER2- breast cancer xenograft models, KAT6-IN-4 demonstrates strong antitumor activity. This compound holds promise for research into KAT6-driven malignancies, such as breast cancer and non-small cell lung cancer.