Sigma-2 Radioligand 2
Sigma-2 Radioligand 2 (compund 4) exhibits low nanomolar affinity (Ki (σ2) =2.30 nM) and high subtype selectivity (Ki (σ1) /Ki (σ2) > 1500) for the σ2 receptor[1].
Product Specifications
CAS Number
2860554-31-8
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sigma-2-radioligand-2.html
Smiles
O=C1N(C2=CC=CC=C2N1CCCCN3CC4=C(C3)C=C(OC)C(OC)=C4)CCF
Molecular Formula
C23H28FN3O3
Molecular Weight
413.49
References & Citations
[1]Wang J, et al. Novel 18F-labeled benzimidazolone-based radioligands as highly selective sigma-2 receptor probes for tumor imaging[J]. Journal of Medicinal Chemistry, 2024, 67 (19) : 17392-17406.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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