Dimenhydrinate
Dimenhydrinate is an orally active H1-antihistamine consisting of Diphenhydramine and 8-Chlorotheophylline. Dimenhydrinate is used to prevent nausea, vomiting, dizziness, and vertigo associated with motion sickness[1].
Product Specifications
CAS Number
523-87-5
UNSPSC
12352005
Hazard Statement
H302
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Dimenhydrinate.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : ≥ 37 mg/mL
Smiles
O=C(N1C)N(C)C2=C(NC(Cl)=N2)C1=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4
Molecular Formula
C24H28ClN5O3
Molecular Weight
469.96
Precautions
H302
References & Citations
[1]Thi-Lien Nguyen, et al. Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice. Neurosci Lett. 2010 Feb 26;471 (1) :38-42.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor
Available Sizes
Frequently Asked Questions
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