(S) -GSK-3685032
(S) -GSK-3685032 is an isomer of GSK-3685032 and serves as a control compound in experiments. GSK-3685032 is a selective inhibitor of DNMT1, characterized by its non-time-dependent, non-covalent, and reversible nature, with an IC50 of 0.036 μM. It induces loss of DNA methylation, transcription activation, and inhibition of cancer cell growth.
Product Specifications
CAS Number
2170142-58-0
Field of Research
Epigenetics & Chromatin
Smiles
C (#N) C1=C (N=C (S[C@H] (C (N) =O) C2=CC=CC=C2) C (C#N) =C1CC) N3CCC (N) CC3
Molecular Formula
C22H24N6OS
Molecular Weight
420.53
Storage Conditions
-20°C
Notes
For research use only.
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