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(S) -GSK-3685032

(S) -GSK-3685032 is an isomer of GSK-3685032 and serves as a control compound in experiments. GSK-3685032 is a selective inhibitor of DNMT1, characterized by its non-time-dependent, non-covalent, and reversible nature, with an IC50 of 0.036 μM. It induces loss of DNA methylation, transcription activation, and inhibition of cancer cell growth.

Product Specifications

CAS Number

2170142-58-0

Field of Research

Epigenetics & Chromatin

Smiles

C (#N) C1=C (N=C (S[C@H] (C (N) =O) C2=CC=CC=C2) C (C#N) =C1CC) N3CCC (N) CC3

Molecular Formula

C22H24N6OS

Molecular Weight

420.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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