DSPE-PEG4-DBCO
DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
2112738-14-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dspe-peg4-dbco.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(CCOCCOCCOCCOCCC(NCCOP(OC[C@H](OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O
Molecular Formula
C71H116N3O15P
Molecular Weight
1282.67
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2128462-01 0.1 mL
Biotin Linked Monoclonal Antibody to Superoxide Dismutase 3, Extracellular (SOD3)
Sign In for Pricing
View Details MBS2128462-02 0.2 mL
Biotin Linked Monoclonal Antibody to Superoxide Dismutase 3, Extracellular (SOD3)
Sign In for Pricing
View Details MBS2128462-03 0.5 mL
Biotin Linked Monoclonal Antibody to Superoxide Dismutase 3, Extracellular (SOD3)
Sign In for Pricing
View Details MBS2128462-04 1 mL
Biotin Linked Monoclonal Antibody to Superoxide Dismutase 3, Extracellular (SOD3)
Sign In for Pricing
View Details