TWEAK-Fn14-IN-1
Product Specifications
Product Name Alternative
ABR-215757; ABR 25757,ABR-215757-d5; ABR 25757-d13
UNSPSC Description
TWEAK-Fn14-IN-1 (Compound L524-0366) is a specific dose-dependent TWEAK-Fn14 inhibitor. TWEAK-Fn14-IN-1 binds specifically to the Fn14 surface with a KD of 7.12 μM. TWEAK-Fn14-IN-1 inhibits TWEAK induced glioma cell migration without any potential cytotoxic effects[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tweak-fn14-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCSCC1)C2=CN(N=N2)C3=CC=CC(Cl)=C3
Molecular Weight
308.79
References & Citations
[1]Tran N, et al. Compositions and methods of screening for compounds that modulate activity at a tweak binding site on a crd of fn14. US20160146784A1
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113763/TWEAK-Fn14-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113763/
Clinical Information
No Development Reported
CAS Number
951612-19-4
Available Sizes
Curated Selection
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